Bone Scintigraphy: Basic Principles, Pitfalls and Pearls
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P: 1-7
March 2022

Bone Scintigraphy: Basic Principles, Pitfalls and Pearls

Nucl Med Semin 2022;8(1):1-7
1. Ege Üniversitesi Tıp Fakültesi, Nükleer Tıp Anabilim Dalı, İzmir, Türkiye
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Publish Date: 15.04.2022
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ABSTRACT

Bone scintigraphy is a preferred examination because of its low cost, easy access and detection of skeletal lesions with high sensitivity. However, since its specificity is low, it is very important to evaluate the findings by considering the clinical history, possible variants and artifacts or mimic lesions. In this review, the basic physiopathological mechanisms that form the basis of imaging in bone scintigraphy, sources of error and pitfalls that should be considered for differential diagnosis in diagnostic evaluation and are frequently encountered are discussed.

References

1Storey G, Murray IPC: Bone scintigraphy: The procedure and interpretation, in Ell PJ, Gambhir SS: Nuclear Medicine in Clinical Diagnosis and Treatment, Vol I. Churchill Livingstone, Elsevier, NewYork, 2004, pp 593-622en.
2Van den Wyngaert T, Strobel K, Kampen WU, et al. The EANM practice guidelines for bone scintigraphy. Eur J Nucl Med Mol Imaging 2016;43:1723-1738.
3Horger M, Bares R. The role of single-photon emission computed tomography/computed tomography in benign and malignant bone disease. Semin Nucl Med 2006;36:286-294.
4Mohd Rohani MF, Zanial AZ, Suppiah S, et al. Bone single-photon emission computed tomography/computed tomography in cancer care in the past decade: a systematic review and meta-analysis as well as recommendations for further work. Nucl Med Commun 2021;42:9-20.
5Stauss J, Hahn K, Mann M, De Palma D. Guidelines for paediatric bone scanning with 99mTc-labelled radiopharmaceuticals and 18F-fluoride. Eur J Nucl Med Mol Imaging 2010;37:1621-1628.
6Aksoy T, Aydın F, Kara Gedik G, et al. TNTD, Çocuklarda Tc-99m ile İşaretli Radyofarmasötikler ve Florit ile Kemik Görüntüleme Kılavuzu 2.0. Nucl Med Semin 2015;1:24-30.
7Bartel TB, Kuruva M, Gnanasegaran G, et al. SNMMI Procedure Standard for Bone Scintigraphy 4.0. J Nucl Med Technol 2018;46:398-404.
8Brown ML, O’Connor MK, Hung JC, Hayostek RJ. Technical aspects of bone scintigraphy. Radiol Clin North Am 1993;31:721-730.
9Gnanasegaran G, Cook G, Adamson K, Fogelman I. Patterns, variants, artifacts, and pitfalls in conventional radionuclide bone imaging and SPECT/CT. Semin Nucl Med 2009;39:380-395.
10Love C, Din AS, Tomas MB, Kalapparambath TP, Palestro CJ. Radionuclide bone imaging: an illustrative review. Radiographics 2003;23:341-358.
11Zuckier LS, Martineau P. Altered biodistribution of radiopharmaceuticals used in bone scintigraphy. Semin Nucl Med 2015;45:81-96.
12Ergün EL, Kiratli PO, Günay EC, Erbaş B. A report on the incidence of intestinal 99mTc-methylene diphosphonate uptake of bone scans and a review of the literature. Nucl Med Commun 2006;27:877-885.
13Pollen JJ, Witztum KF, Ashburn WL. The flare phenomenon on radionuclide bone scan in metastatic prostate cancer. AJR Am J Roentgenol 1984;142:773-776.
14Loutfi I, Collier BD, Mohammed AM. Nonosseous abnormalities on bone scans. J Nucl Med Technol 2003;31:149-153; quiz 154-6.
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