ABSTRACT
Cardiovascular diseases are the leading causes of mortality and morbidity worldwide and account for the substantial proportion of global health burden. Since early diagnosis and treatment are important in disease course, numerous preclinical studies are being conducted to develop diagnostic and therapeutic alternatives. In preclinical studies, small or large animal models of cardiovascular diseases are created using surgical methods or toxic agents to the cardiovascular system. Imaging is essential in these models. Imaging of animal models provides a non-invasive way of evaluating the biological structure in vivo with scintigraphic methods and positron emission tomography being used often.
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