Molecular Imaging in Hepatocellular Carcinoma
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Review
P: 170-180
July 2024

Molecular Imaging in Hepatocellular Carcinoma

Nucl Med Semin 2024;10(2):170-180
No information available.
No information available
Online Date: 31.07.2024
Publish Date: 31.07.2024
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Abstract

Hepatocellular carcinomas (HCCs) are clinically and pathologically heterogeneous tumors that exhibit resistance to chemotherapy and have aggressive characteristics. The most commonly used positron emission tomography (PET) radiopharmaceutical, Fluorine-18 (F-18) fluorodeoxyglucose (FDG), has been disappointing in the evaluation of HCC. This disappointment has led to studies using various radiopharmaceuticals such as choline derivatives, acetate, and prostate-specific membrane antigen, which complement and/or enhance the role of FDG. This article aims to examine the various PET radiopharmaceuticals used for HCC imaging and the specific pathways these agents target in HCC and liver cancers.

Keywords:
Hepatocellular carcinoma
positron emission tomography
PSMA
choline
FDG
FAPI

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