Nuclear Medicine in Urinary Tract İnfection
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Review
P: 179-185
December 2019

Nuclear Medicine in Urinary Tract İnfection

Nucl Med Semin 2019;5(3):179-185
1. Hacettepe Üniversitesi Tıp Fakültesi, Nükleer Tıp Ana Bilim Dalı, Ankara, Türkiye
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Publish Date: 05.12.2019
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ABSTRACT

Urinary tract infections (UTIs) are frequent in pediatric population and have various clinical presentations. Definitive diagnosis is made by urinalysis and quantitative urine culture, and antibiotic treatment is usually sufficient in uncomplicated UTI cases. However, patients that have co-morbidities, congenital urinary tract anomalies, or bowel-urinary bladder dysfunction can present with recurrent infections. These patients should be investigated using renal ultrasonography, Tc-99m dimercaptosuccinic acid cortical renal scintigraphy, or voiding cystourethrography. The patient management using these imaging tools varies worldwide. This review aims to underline the strength and differences among the current guidelines on UTI.

References

1Marild S, Jodal U. Incidence rate of first-time symptomatic urinary tract infection in children under 6 years of age. Acta Paediatr 1998;87:549-552.
2Shaikh N, Ewing AL, Bhatnagar S, Hoberman A. Risk of renal scarring in children with a first urinary tract infection: a systematic review. Pediatrics 2010;126:1084-1091.
3Loening-Baucke V. Urinary incontinence and urinary tract infection and their resolution with treatment of chronic constipation of childhood. Pediatrics 1997;100:228-232.
4Treves ST, Baker A, Fahey FH, et al. Nuclear medicine in the first year of life. J Nucl Med 2011;52:905-925.
5Lassmann M, Treves ST, Group ESPDHW. Paediatric radiopharmaceutical administration: harmonization of the 2007 EANM paediatric dosage card (version 1.5.2008) and the 2010 North American consensus guidelines. Eur J Nucl Med Mol Imaging 2014;41:1036-1041.
6Piepsz A, Colarinha P, Gordon I, et al. Guidelines for Tc-99m-DMSA scintigraphy in children. Eur J Nucl Med 2001;28:BP37-41.
7Weyer K, Nielsen R, Petersen SV, Christensen EI, Rehling M, Birn H. Renal uptake of Tc-99m-dimercaptosuccinic acid is dependent on normal proximal tubule receptor-mediated endocytosis. J Nucl Med 2013;54:159-165.
8Christensen EI, Gburek J. Protein reabsorption in renal proximal tubule-function and dysfunction in kidney pathophysiology. Pediatr Nephrol 2004;19:714-721.
9Lee BH, Lee SH, Choi HJ, et al. Decreased renal uptake of (99m)Tc-DMSA in patients with tubular proteinuria. Pediatr Nephrol 2009;24:2211-2216.
10Risdon RA, Godley ML, Parkhouse HF, Gordon I, Ransley PG. Renal pathology and the Tc-99m-DMSA image during the evolution of the early pyelonephritic scar: an experimental study. J Urol 1994;151:767-773.
11Jakobsson B, Berg U, Svensson L. Renal scarring after acute pyelonephritis. Arch Dis Child 1994;70:111-115.
12Hoberman A, Charron M, Hickey RW, Baskin M, Kearney DH, Wald ER. Imaging studies after a first febrile urinary tract infection in young children. N Engl J Med 2003;348:195-202.
13Olbing H, Claesson I, Ebel KD, et al. Renal scars and parenchymal thinning in children with vesicoureteral reflux: a 5-year report of the International Reflux Study in Children (European branch). J Urol 1992;148:1653-1656.
14Piepsz A, Tamminen-Mobius T, Reiners C, et al. Five-year study of medical or surgical treatment in children with severe vesico-ureteral reflux dimercaptosuccinic acid findings. International Reflux Study Group in Europe. Eur J Pediatr 1998;157:753-758.
15Swerkersson S, Jodal U, Sixt R, Stokland E, Hansson S. Urinary tract infection in small children: the evolution of renal damage over time. Pediatr Nephrol 2017;32:1907-1913.
16Orellana P, Baquedano P, Rangarajan V, et al. Relationship between acute pyelonephritis, renal scarring, and vesicoureteral reflux. Results of a coordinated research project. Pediatr Nephrol 2004;19:1122-1126.
17Urinary tract infection in children: diagnosis, treatment and long-term management. 2007 (updated in 2017). Accessed date: 2019 september 1st 2019. Available from: www.nice.org.uk/CG054fullguideline.
18Gordon I, Barkovics M, Pindoria S, Cole TJ, Woolf AS. Primary vesicoureteric reflux as a predictor of renal damage in children hospitalized with urinary tract infection: a systematic review and meta-analysis. J Am Soc Nephrol 2003;14:739-744.
19Moorthy I, Easty M, McHugh K, Ridout D, Biassoni L, Gordon I. The presence of vesicoureteric reflux does not identify a population at risk for renal scarring following a first urinary tract infection. Arch Dis Child 2005;90:733-736.
20Cheng CH, Tsau YK, Kuo CY, Su LH, Lin TY. Comparison of extended virulence genotypes for bacteria isolated from pediatric patients with urosepsis, acute pyelonephritis, and acute lobar nephronia. Pediatr Infect Dis J 2010;29:736-740.
21Martinell J, Lidin-Janson G, Jagenburg R, Sivertsson R, Claesson I, Jodal U. Girls prone to urinary infections followed into adulthood. Indices of renal disease. Pediatr Nephrol 1996;10:139-142.
22Baltu D. DMSA Sintigrafisi ile renal skar tespit edilen hastaların uzun dönem izlemi Ankara: Hacettepe Universitesi; 2018
23Geback C, Hansson S, Martinell J, Sandberg T, Sixt R, Jodal U. Renal function in adult women with urinary tract infection in childhood. Pediatr Nephrol 2015;30:1493-1499.
24Geback C, Hansson S, Himmelmann A, Sandberg T, Sixt R, Jodal U. Twenty-four-hour ambulatory blood pressure in adult women with urinary tract infection in childhood. J Hypertens 2014;32:1658-1664; discussion 1664.
25American College of RadiologyACR Appropriateness Criteria®Acute Pyelonephritis (revised in 2018). Accessed date: september 1st 2019. Available from: www.acr.org/ac.
26Robinson JL, Finlay JC, Lang ME, Bortolussi R, Canadian Paediatric Society ID, Immunization Committee CPC. Urinary tract infections in infants and children: Diagnosis and management. Paediatr Child Health 2014;19:315-325.
27Subcommittee On Urinary Tract I. Reaffirmation of AAP Clinical Practice Guideline: The Diagnosis and Management of the Initial Urinary Tract Infection in Febrile Infants and Young Children 2-24 Months of Age. Pediatrics 2016;138.
28Stein R, Dogan HS, Hoebeke P, et al. Urinary tract infections in children: EAU/ESPU guidelines. Eur Urol 2015;67:546-558.
29Wan CH, Tseng JR, Lee MH, Yang LY, Yen TC. Clinical utility of FDG PET/CT in acute complicated pyelonephritis-results from an observational study. Eur J Nucl Med Mol Imaging 2018;45:462-470.
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