Abstract

Thyroid scintigraphy remains one of the cornerstone imaging modalities in nuclear medicine for the diagnosis and management of thyroid diseases, owing to its unique ability to simultaneously assess both the morphological structure and functional status of the thyroid gland. This guideline has been developed to ensure procedural standardization in thyroid scintigraphy, optimize image quality, and establish a common, consistent terminology for image interpretation. The guideline comprehensively addresses all stages of thyroid scintigraphy, ranging from patient preparation and radiopharmaceutical selection to imaging protocols and reporting criteria, based on current international literature and recent technological advances. In addition to conventional planar imaging techniques, the diagnostic contribution of a hybrid imaging modality such as single-photon emission computed tomography/computed tomography is emphasized due to its ability to integrate anatomical and functional information in selected clinical scenarios. This framework aims to serve as an evidence-based, up-to-date, and practical reference for nuclear medicine physicians, referring clinicians, and healthcare professionals, directly supporting clinical decision-making in routine practice.