ABSTRACT

Neuroendocrine tumors are a heterogeneous group of neoplasms with various clinical and imaging findings and there has been significant developments in diagnosis in recent years. On the other hand, a significant number of patients are still diagnosed after metastasis. However, this situation often does not constitute an obstacle for curative treatment. Tumor burden assessment usually requires the use of multiple imaging modalities, including computed tomography, magnetic resonance imaging, ultrasound, and somatostatin receptor-based imaging. Accurate staging is the most important factor in treatment planning. For this reason, accurate imaging is one of the indispensable steps for diagnosis, staging, treatment plan and follow-up. Various imaging techniques have been developed and optimized to accurately assess tumor burden in these patients. Morphological and functional imaging methods, which are basically considered in two classes, developed for this purpose and are often used in combination. In this article, current radiological imaging methods and findings used in the diagnosis of neuroendocrine tumors will be reviewed.