Response Evaluation with PET/CT and Radiotherapy Planning in Hodgkin Lymphoma Treatment
PDF
Cite
Share
Request
Review
P: 178-181
November 2023

Response Evaluation with PET/CT and Radiotherapy Planning in Hodgkin Lymphoma Treatment

Nucl Med Semin 2023;9(3):178-181
1. Ege Üniversitesi Tıp Fakültesi, Radyasyon Onkolojisi Anabilim Dalı, İzmir, Türkiye
No information available.
No information available
Publish Date: 28.12.2023
PDF
Cite
Share
Request

ABSTRACT

Lymphomas are a broad group of diseases arising from different types of lymphocytes. Over the last half decade, successive advances in treatment possibilities have led to an improvement in patient prognosis from fatal outcomes to a clinical situation where cure can be achieved. High rates of disease control and long-term survivors. Positron emission tomography/computed tomography based imaging plays an important role in staging and optimal evaluation of treatment response. The location, technique and dose selection of radiotherapy, which is an indispensable treatment method especially in lymphoma patients, are determined according to the status of functional imaging after chemotherapy. The International Lymphoma Radiation Oncology Group develops guidelines for the optimal use of imaging. The transition from uniform large-area treatment volumes to complex individual setups that take into account biological response assessments based on functional imaging allows for further reductions in side effects.

References

1
Zelenetz A, Gordon LI, Abramson JS, et al. NCCN clinical practice guidelines in oncology: B-cell lymphomas, version 6.2023 NCCN Guidelines 2023.
2
Hoppe RT, Advani R, Ai WZ, et al. NCCN clinical practice guidelines in oncology: Hodgkin lymphoma, version 6.2023 NCCN Guidelines 2022.
3
Horwitz SM, Ansell S, Ai WZ, et al. NCCN clinical practice guidelines in oncology: T-cell lymphoma, version 6.2023 NCCN Guidelines 2023.
4
Illidge T, Specht L, Yahalom J, et al. Modern radiation therapy for nodal non-Hodgkin lymphoma-target definition and dose guidelines from the International Lymphoma Radiation Oncology Group. Int J Radiat Oncol Biol Phys 2014; 89:49-58.
5
Yahalom J, Illidge T, Specht L, et al. Modern radiation therapy for extranodal lymphomas: field and dose guidelines from the International Lymphoma Radiation Oncology Group. Int J Radiat Oncol Biol Phys 2015; 92:11-31.
6
Specht L, Yahalom J, Illidge T, et al. Modern radiation therapy for Hodgkin lymphoma: field and dose guidelines from the international lymphoma radiation oncology group (ILROG). Int J Radiat Oncol Biol Phys 2014;89:854-862.
7
Constine L, Yahalom J, Ng A, et al. The role of radiation therapy in patients with relapsed or refractory Hodgkin lymphoma: Guidelines from the International Lymphoma Radiation Oncology Group. Int J Radiat Oncol Biol Phys 2018;100:1100-1118.
8
Ng AK, Yahalom J, Goda JS, et al. Role of radiation therapy in patients with relapsed/refractory diffuse large B-cell lymphoma: Guidelines from the International Lymphoma Radiation Oncology Group. Int J Radiat Oncol Biol Phys 2018;100:652-669.
9
Pepper NB, Oertel M, Rehn S, Kobe C, Eich HT. Modern PET-Guided Radiotherapy Planning and Treatment for Malignant Lymphoma. Semin Nucl Med 2023;53:389-399.
10
Cheson BD, Fisher RI, Barrington SF, et al. Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non- Hodgkin lymphoma: the Lugano classification. J Clin Oncol 2014;32:3059-3068.
11
Barrington SF, Mikhaeel NG, Kostakoglu L, et al. Role of imaging in the staging and response assessment of lymphoma: consensus of the International Conference on Malignant Lymphomas Imaging Working Group [published correction appears. J Clin Oncol 2014;32:3048-3058.
12
Terezakis SA, Sch€oder H, Kowalski A, et al. A prospective study of 1⁸FDG-PET with CT co-registration for radiation treatment planning of lymphomas and other hematologic malignancies. Int J Radiat Oncol Biol Phys 2014;89:376-383.
13
Metser U, Prica A, Hodgson DC, et al. Effect of PET/CT on the Management and Outcomes of Participants with Hodgkin and Aggressive Non- Hodgkin Lymphoma: A Multicenter Registry. Radiology 2019;290:488-495.
14
Freeman CL, Savage KJ, Villa DR, et al. Long-term results of PET-guided radiation in patients with advanced-stage diffuse large B-cell lymphoma treated with R-CHOP. Blood 2021;137:929-938.
15
Fuchs M, Goergen H, Kobe C, et al. Positron Emission Tomography-Guided Treatment in Early-Stage Favorable Hodgkin Lymphoma: Final Results of the International, Randomized Phase III HD16 Trial by the German Hodgkin Study Group. J Clin Oncol 2019;37:2835-2845.
16
Andre MPE, Girinsky T, Federico M, et al. Early Positron Emission Tomography Response-Adapted Treatment in Stage I and II Hodgkin Lymphoma: Final Results of the Randomized EORTC/LYSA/FIL H10 Trial. J Clin Oncol 2017;35:1786-1794.
17
Terezakis SA, Hunt MA, Kowalski A, et al. [1⁸F]FDG-positron emission tomography co-registration with computed tomography scans for radiation treatment planning of lymphoma and hematologic malignancies. Int J Radiat Oncol Biol Phys 2011;81:615-622.
18
Rehn S, Pixberg M, Reinartz G, et al. 18F-FDG PET-CT in Radiotherapy of localized Follicular Lymphoma. Angewandte Nuklearmedizin 2022;45:47-55.