ABSTRACT
Radiotherapy is a fundamental modality in today’s modern cancer treatment, with about half of all cancer patients undergoing radiotherapy at some stage in their treatment. Determination of the optimal target volume and precise application of the dose prescribed to it constitute the basic principles of modern radiotherapy. Positron emission tomography/computed tomography (PET/CT) has made significant contributions not only to nuclear medicine but also in the field of radiation oncology. It has enhanced the accuracy and precision of target volume determination, thereby reducing the risk of normal tissue toxicity. Additionally, PET/CT enables the identification of areas within the tumor that exhibit metabolic heterogeneity, allowing for tailored treatment strategies. In this review, the contributions of PET/CT to the discipline of radiation oncology will be evaluated by dividing it into subheadings according to tumor types.